Senior Scientist– Cell/bio Assays

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Commit Biologics

Aarhus

Black Swans Exist | Recruiting talents for Commit Biologics

 

Are you dreaming of shaping a new biotech company and developing curative treatment to cancer? Are you highly experienced in discovery of VH or VHH antibody based multi-specific formats from biotech or large pharma and want to use your capacity to catalyze a new way to utilize the immune system to treat cancer? – then read on.

 

About Commit Biologics

Commit is a newly established biotech company with a proprietary technology for utilizing the immune complement system in cancer treatment.

We are an experienced team of science and business leaders with the vision to provide curative treatment to those cancer patients, for whom no treatment is available today. Our BICE technology utilizes the complement system to kill tumor cells through the use of single domain antibody based bispecifics.

 

The position

We are seeking a lab based creative, self-motivated, detail-oriented and highly experienced scientist with a proven background in development and validation of immune- and cell-based assays.

You will be responsible for the identification, development, and implementation of novel immunology cell-based assays around complement activity in its broadest sense. This will include the planning, design and execution of experiments, data analysis and interpretation, preparation of reports and communication of the findings to the team and stakeholders. Additional responsibilities will include providing technical training and coaching to more junior team members where required.

 

Your core responsibilities will be to:

  • Develop and execute cell based functional (potency) assays:
  • Screening and characterization of the pharmacology of the BiCE constructs using the above methods
  • Establishment and implementation of FACS panels for in vitro and in vivo immunophenotyping.

 

In addition, you will shape Commit Biologics together with us to establish a professional and cutting-edge immune therapy company.

 

Qualifications

You hold a PhD or MS degree and have at least 7 to 10 years of experience with immunology, FACS and cell-based assays in the pharmaceutical or biotech industry.

We are looking for a candidate with these qualifications:

Scientific skills:

  • Excellent lab-based scientist
  • Possession of a deep technical expertise and hands-on knowledge in immunology and cell based assays and methods that can be applied to cancer immunology research such as
    • PBMC isolation and isolation of specific immune cell types
    • CDC, ADCP, ADCC assays
    • Cell migration, proliferation and activation assays using immune cells
    • Fluorescence-activated cell sorting (FACS)
    • Tissue culture techniques for cell-based immunoassays, experience working with human immune cells, ex vivo immunobiology techniques such as: complex multiparameter flow cytometry (including intracellular cytokine or multicolor cell surface staining)
  • Understanding and enthusiasm for tumor immunology and cancer therapies
  • Provide technical and operational expertise to stakeholders to ensure the delivery of high-quality assays for data generation throughout project life
  • Data processing, statistical analysis and interpretation

Soft skills:

  • Highly motivated and dynamic individual who can take ownership of a project and take pride in its delivery.
  • Proactive with problem-solving aptitude
  • The ability to plan and execute to clear timelines and to prioritize tasks
  • The ability to work independently and actively collaborate within and across teams
  • Excellent communication and organizational skills
  • Excellent command of the English language
  • Strong results driven personality, high level of enthusiasm, energy and creativity and an ability to demonstrate flexibility and integrity

 

Familiarity with any of the following would be an advantage:

  • In vivo tumor model systems to evaluate the efficacy/ activity of BiCE molecules (syngeneic tumor models, humanized mouse models, etc)
  • Complement system biology
  • Immuno oncology biology
  • Experienced in the use of DOE statistical analysis
  • Antibody fragment, Nanobody/dab characterization
  • Knowledge and experience with various HPLC/UPLC analytical techniques
  • Any other experience relevant to antibody discovery & engineering
  • Experience with working with CRO

 

Join us

We offer you to become part of a fun and professional team, shaping the future of Commit Biologics and creating curative treatment to cancer patients. Give us a call to discuss more if your heart is beating faster than usual and you are ready for a new endeavor.

The job is located in Aarhus, Denmark. (Among TIME magazine’s “Worlds greatest places of 2023” https://time.com/collection/worlds-greatest-places-2023/6261658/aarhus-denmark/)

 

 

 

Contact

If you want to hear more about this opportunity and Commit Biologics, or if you have any questions regarding the position, please do not hesitate to contact us. If you wish to apply for the position, please send an updated version of your CV, together with what questions you might have, and we will get in touch with you soon.

2022_09_05_BSE_Portraits4815

Annika Kamm

Consultant

Talent Engagement

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